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AssigneeKumiai Chemical Industry Co., Ltd.
InventorsEisuke Ishihara, Hiroshi Yonehara, Katsuyuki Akasaki, Masao Minowa, Katsumi Kobayashi
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The present invention relates to a method of cultivation and extraction of multhiomycin, an antibiotic, and relates also to a veterinary medicine containing multhiomycin as an effective ingredient and more particularly, the present invention provides a method for obtaining multhiomycin by cultivating a multhiomycin-producing fungus such as Streptomyces sp. 8446-CC1 belonging to genus Streptomyces in a culture medium containing a sulfur-containing amino acid and treating the culture medium with a mixed solvent of alcohols and halogenated hydrocarbons or ketones and provides a medicine for promoting growth of animals and preventing various kinds of diseases of animals which contains multhiomycin as an essential component.
The method for preparing multhiomycin which comprises cultivating a multhiomycin producing strain belonging to the genus Streptomyces in a sulfur-containing carboxylic acid-containing liquid culture medium, said acid being selected from the group consisting of cystine and methionine which is present in an amount of 0.01-5 weight percent and isolating said multhiomycin.
Dependencies are inferred from the claim text.