Method for producing antibiotic C-15003 P-4
AssigneeTakeca Chemical Industries, Ltd.
InventorsEiji Higashide, Kazunori Hatano, Mitsuko Asai
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Abstract
A novel Antibiotic C-15003 P-4 is specifically produced by cultivating a microorganism of the genus Nocardia in a culture medium containing leucine and/or its derivatives. The Antibiotic C-15003 P-4 is useful as an antifungal agent, antiprotozoan agent and antitumor agent.
Claims3
In a method for producing Antibiotic C-15003 P-4 by cultivating a microorganism belonging to the genus Nocardia and being capable of producing Antibiotic C-15003 P-4 in a culture medium containing assimiable carbon sources and digestible nitrogen sources, wherein the improvement comprises incorporating about 0.01 to 1% by weight based on the volume of the culture medium of leucine, .alpha.-ketoisocaproic acid or its salt, or an ester, amide or salt of leucine as additive substances into the culture medium.
Dependencies are inferred from the claim text.