Naphthaquinone anti-psoriatic agents
AssigneeSyntex (U.S.A.) Inc.
InventorsGordon H. Jones, John Young
Life of this patent
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Abstract
Psoriasis in mammals is relieved by topically administering substituted naphthaquinones of the formula: ##STR1## where R.sup.1 and R.sup.2 are the same or different and are hydrogen, hydroxy, alkoxy or acylamino and R.sup.3 is hydrogen, halo, cyano or alkoxy with the proviso that R.sup.1 and R.sup.2 are not both hydrogen.
Claims8
A method for relieving the condition of psoriasis which comprises topically administering to mammals in need thereof an amount of a compound of the formula ##STR10## where R.sup.1 and R.sup.2 are the same or different and are hydrogen, hydroxy or C.sub.1 to C.sub.18 linear or branched alkoxy and R.sup.3 is hydrogen, halo, cyano or C.sub.1 to C.sub.18 linear or branched alkoxy, with the proviso that R.sup.1 and R.sup.2 are not both hydrogen, sufficient to relieve the condition of psoriasis in mammals in combination with a pharmaceutically acceptable, non-toxic carrier suitable for said administration form.
Dependencies are inferred from the claim text.