Substituted 5,6-dimethylpyrrolo[2,3-d]pyrimidine compounds, their production and their medicinal use
AssigneeBayer Aktiengesellschaft
InventorsHermann J. Roth, Kurt Eger, Sedika Issa, Haireddin Jacobi
Life of this patent
Estimating the term…
Abstract
The invention includes 5,6-dimethylpyrrolo [2,3-d]-pyrimidines (and method for their manufacture) of the formula ##STR1## or an acid-addition salt thereof, in which R is amino or hydroxy, R.sub.1 is halogen, nitro, C.sub.1 --C.sub.6 alkyl or alkoxy or CF.sub.3 and, where R is hydroxy, is also hydrogen, R.sub.2 is hydrogen, halogen or C.sub.1 --C.sub.6 -alkyl or alkoxy, and n is 1 or 2. Also included in the invention are pharmaceutical compositions containing said pyrrolo [2,3-d]-pyrimidines and the use of said compounds and compositions for treating CNS illnesses or inflammations.
Claims13
A 5,6-dimethylpyrrolo[2,3-d]pyrimidine compound of the formula ##STR20## or a physiologically acceptable acid-addition salt thereof, in which R denotes amino or hydroxyl,
- R.sub.1 denotes halogen, nitro,
- C.sub.1 to C.sub.6 alkyl or trifluoromethyl, and in the case where R is hydroxyl, also denotes hydrogen,
- R.sub.2 in each case denotes hydrogen,
- halogen or C.sub.1 to C.sub.6 alkyl or alkoxy and
- n is 1 or 2.
Dependencies are inferred from the claim text.