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US 4,229,436 AGranted
Antibiotic G-6302
AssigneeTakeda Chemical Industries, Ltd.
InventorsAkira Imada, Kazuaki Kitano, Mitsuko Asai
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Abstract
A novel Antibiotic G-6302 is produced by cultivating a microorganism belonging to the genus Pseudomonas and being capable of producing Antibiotic G-6302 in a culture medium to have Antibiotic G-6302 elaborated and accumulated in the cultured broth and recovering the antibiotic. Antibiotic G-6302 is useful as a germicide or disinfectant.
Claims3
A member selected from the group consisting of Antibiotic G-6302 having the following characteristics, and a metal or ammonium salt thereof:
- (1) Melting point:
- 120.degree. C. (sintering), 130.degree. C. (decomp.)
- (2) Appearance:
- white powder
- (3) Elemental analysis:
- (%) C 34.99, .+-.0.5;
- H 5.58, .+-.0.5;
- N 13.30, .+-.0.5;
- O 38.13, .+-.0.5;
- S 7.70, .+-.0.5 (as dried at 40.degree. C. for 6 hours over phosphorus pentoxide under reduced pressure)
- (4) Ultraviolet absorption spectrum:
- No characteristic absorptions over 210 nm
- (5) Infrared absorption spectrum [KBr, dominant absorptions (wave-numbers, cm.sup.-1)]:
- 1770, 1650, 1530, 1240, 1043
- (6) Specific rotation:
- [.alpha]sub.D.sup.23 +94.degree..+-.10.degree. (c=0.35, H.sub.2 O)
- (7) Solubility:
- Insoluble in petroleum ether, hexane, diethyl ether, benzene, ethyl acetate and chloroform;
- sparingly soluble in ethanol, pyridine and acetone;
- soluble in methanol and dimethylsulfoxide;
- and readily soluble in water
- (8) Basicity, neutrality or acidity:
- Acid
- (9) Molecular weight:
- 400.+-.20 (by titrometry)
- (10) Color reactions:
- Positive:
- ninhydrin and potassium permanganate reactions;
- negative:
- ferric chloride-potassium ferricyanate, Sakaguchi and Molisch reactions;
- doubtful positive:
- Ehrlich reaction.
29 more elements
Dependencies are inferred from the claim text.