Galenical form of administration of betahistine and its derivatives
OwnerJean S. Cherqui, Alain C. Djianeinventors
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OwnerJean S. Cherqui, Alain C. Djianeinventors
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There is provided a medicament in a form having surprising effectiveness against vertigo in Meniere's syndrome. This medicament comprises, as active ingredient, betahistinemethanesulfonate. The medicament further comprises a core of pharmaceutially acceptable thereapeutically inert carrier material having the active ingredient absorbed thereon, said active ingredient being covered with a dialysis membrane said membrane further carrying a second layer of active ingredient which, if desired, is itself absorbed upon a layer of therapeutically inert carrier material and is covered with a further dialysis membrane. There may be utilized a plurality of substantially concentric layers of active material suitably absorbed on the carrier, and covered with a dialysis membrane to provide a long-acting medicament form.
A therapeutically useful and pharmacologically acceptable oral depot medicament in the form of substantially uniformally sized spheroidal particles containing 2-methylaminoethyl pyridinemethanesulfonate as the active ingredient thereof comprising
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