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US 4,229,363 AGranted
4-Hydroxy-3-(substitutedmethyl)-benzeneacetic acids
AssigneeYeda Research and Development Co. Ltd.
InventorsAbraham Nudelman, Abraham Patchornik
Life of this patent
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Abstract
New 4-hydroxy-3-(substitutedmethyl)benzeneacetic acids have been prepared which are useful as starting materials in the preparation of cephalosporin and penicillin derivatives.
Claims9
A compound selected from the formula ##STR11## wherein W is hydrogen;
- hydroxy;
- SO.sub.3 H or --COOR.sub.1 wherein R.sub.1 is selected from hydrogen, phenyl or 5-indanyl, or a 1 to 4 carbon alkyl group;
- --NHR.sub.2 wherein R.sub.2 is hydrogen, tert-butyloxycarbonyl, ##STR12## wherein R.sub.3 is hydrogen, a lower alkyl group of from 1 to 4 carbon atoms or a phenyl group;
- X is an alkoxy group of from 1 to 4 carbon atoms;
- X is --SCN;
- or an acceptable salt thereof.
3 more elements
Dependencies are inferred from the claim text.