Horizontal flow-through coil planet centrifuge
AssigneeThe United States of America as represented by the Department of Health, Education and Welfare
InventorYoichiro Ito
Life of this patent
Estimating the term…
Abstract
A horizontal flow-through coil planet centrifuge wherein flow-through separation columns are rotatably mounted on both sides of a rotor formed by a pair of spaced parallel rotary wings, with suitable intercoupling to avoid the need for rotary seals. Fluid circuit and adjustable valving arrangements are provided for (1) allowing two separations to be simultaneously performed, (2) for connecting the two columns in series to double the partition efficiency, or (3) using one column to separate samples in an ordinary manner while a desired portion of the eluate can be introduced into the second column to recycle.
Claims15
A horizontal flow-through coil planet centrifuge apparatus comprising a support, a stationary shaft member horizontally rigidly mounted in said support, a pair of spaced parallel wing members, means rotatably supporting said wing members on said shaft member perpendicularly thereto, respective horizontal separation column assemblies journalled respectively for independent, planetary motions between portions of said wing members located on opposite sides of said shaft member, respective inlet and outlet flow tubes connected to each of said column assemblies to define flow paths therethrough, and means to simultaneously rotate said column assemblies around their rotational axes relative to said wing members and to revolve said wing members around said shaft member at relative rates and directions to avoid twisting of the flow tubes.
A horizontal flow-through centrifuge apparatus of the coil planet type comprising a support, a shaft member horizontally rigidly mounted on said support, a pair of spaced parallel wing members, means rotatably supporting said wing members on said shaft member perpendicularly thereto, respective horizontal separation in column assemblies journalled respectively for independent, planetary motions between portions of said wing members located on opposite sides of said shaft member, respective inlet and outlet flow tubes connected to each of said column assemblies to define flow paths therethrough, means to simultaneously rotate said column assemblies around their rotational axes relative to said wing members and to revolve said wing members around said shaft members, and fluid circuit means connected to said flow tubes and including changeable means to selectively provide at least two different fluid circuit configurations containing the separation column assemblies.
A horizontal flow-through centrifuge apparatus of the coil planet type comprising a support, a shaft member horizontally rigidly mounted on said support, a pair of spaced parallel wing members, means rotatably supporting said wing members on said shaft member perpendicularly thereto, respective horizontal separation column assemblies journalled between portions of said wing members located on opposite sides of said shaft member, respective inlet and outlet flow tubes connected to each of said column assemblies to define flow paths therethrough, means to simultaneously rotate said column assemblies around their rotational axes relative to said wing members and to revolve said wing members around said shaft member, and fluid circuit means connected to said flow tubes and including changeable means to selectively provide at least two different fluid circuit configurations containing the separation column assemblies, and wherein said changeable means comprises respective multi-position valves connected with said column assemblies.
A horizontal flow-through centrifuge apparatus of the coil planet type comprising a support, a shaft member horizontally rigidly mounted on said support, a pair of spaced parallel wing members, means rotatably supporting said wing members on said shaft member perpendicularly thereto, respective horizontal separation column assemblies journalled between portions of said wing members located on opposite sides of said shaft member, respective inlet and oultet flow tubes connected to each of said column assemblies to define flow paths therethrough, means to simultaneously rotate said column assemblies around their rotational axes relative to said wing members and to revolve said wing members around said shaft member, and fluid circuit means connected to said flow tubes and including changeable means to selectively provide at least two different fluid circuit configurations containing the separation column assemblies, and wherein one of said fluid circuit configurations includes means to enable said separation column assemblies to operate independently of each other and the other fluid circuit configuration includes means to connect said separation column assemblies in series.
Dependencies are inferred from the claim text.