Pyrano[4,3-e]-as-triazines and corresponding 4-oxides
AssigneeSandoz Ltd.
InventorGregory B. Bennett
Life of this patent
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Abstract
This disclosure describes novel compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 each independently represent hydrogen, halo having an atomic weight of about 19 to 36, lower alkyl, straight chain lower alkoxy, amino, nitro or trifluoromethyl, and X represents ##STR2## which are useful as minor tranquilizers and sleep inducers.
Claims26
A compound of the formula ##STR14## wherein R.sub.1 and R.sub.2 each independently represent hydrogen, halo having an atomic weight of about 19 to 36, lower alkyl, straight chain lower alkoxy, amino, nitro or trifluoromethyl, and
- X represents ##STR15## provided that (i) when one of R.sub.1 and R.sub.2 represents nitro, the other is other than nitro or trifluoromethyl;
- (ii) when R.sub.1 and R.sub.2 represent trifluoromethyl, they are on other than adjacent carbon atoms;
- and
- (iii) when R.sub.1 and R.sub.2 represent t-butyl, they are on other than adjacent carbon atoms, and
- (iv) when one of R.sub.1 and R.sub.2 is trifluoromethyl and the other is t-butyl, they are on other than adjacent carbon atoms.
A compound of the formula ##STR20## wherein R.sub.1 ' is hydrogen, halo having an atomic weight of about 19 to 36, lower alkyl, straight chain lower alkoxy, or amino,
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.