Novel phenethylamine derivatives and processes for preparing same
AssigneeTanabe Seiyaku Co., Ltd.
InventorsTasaburo Kiguchi, Kimiaki Hayashi, Isao Yamaguchi
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Abstract
A compound of the formula: ##STR1## wherein R is methyl or 2-methylthioethyl, is prepared by either (A) condensing a compound of the formula: ##STR2## wherein R is the same as above, or a reactive derivative thereof with 3,4-diethoxycarboxyphenethylamine, or (B) condensing the compound (II) or a reactive derivative thereof with dopamine, followed by reacting the resultant product with an ethoxycarbonyl halide. The compound (I) shows potent renal blood flow-increasing activity and is useful for the treatment of renal hypertension, congestive heart failure and other diseases due to renal blood flow disturbances.
Claims5
A compound of the formula:
- ##STR6## wherein R is methyl or 2-methylthioethyl.
A pharmaceutical composition for increasing renal blood flow activity which comprises a compound of the formula:
- ##STR7## wherein R is methyl or 2-methylthioethyl, in an amount sufficient to provide a therapeutic effect when administered, and a pharmaceutically acceptable carrier therefor.
Dependencies are inferred from the claim text.