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US 4,227,002 AGranted
Halo-A-23187 derivatives
AssigneeEli Lilly and Company
InventorsDonner F. Babcock, Charles M. Deber, Manuel Debono, R. Michael Molloy, Douglas R. Pfeiffer
Life of this patent
Estimating the term…
Abstract
Halo-A-23187 derivatives, prepared by reaction of antibiotic A-23187 with an N-halo-type halogenating agent, and salts thereof, which are (1) useful biochemical tools for the study of transport of ions in cellular systems, (2) useful chemical tools for removal and recovery of ions, and (3) potential cardiotonic agents.
Claims7
A compound selected from a group consisting of compounds having the following formulas:
- ##STR5## wherein R is bromine or chlorine;
- ##STR6## and the pharmaceutically acceptable cationic salts of (1), (2) and (3).
Dependencies are inferred from the claim text.