Antibacterial compounds
AssigneeBeecham Group Limited
InventorsNorman H. Rogers, Peter J. O'Hanlon
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Abstract
A compound of formula (II), named pseudomonic acid C or a salt or ester thereof: ##STR1## has antibacterial and anti-mycoplasma activity, and can be produced either by fermentation of Pseudomonas fluorescens, or by de-oxygenation of pseudomonic acid A, the compound having an epoxide in place of the double bond. The compounds are therefore useful in the treatment of human and veterinary bacterial and mycoplasma-induced infections.
Claims12
A pharmaceutical or veterinary composition comprising an antibacterially effective amount of a compound selected from the group consisting of an acid of the formula:
- ##STR12## , a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable ester thereof in combination with a pharmaceutically or veterinary acceptable carrier.
The method of treating human or veterinary bacterial or mycoplasma-induced infections therapeutically or prophylactically which comprises administering to a human or veterinary aninal respectively an antibacterially effective amount of a compound selected from the group consisting of an acid of the formula:
- ##STR13## , a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable ester thereof.
Dependencies are inferred from the claim text.