N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides
AssigneeA. H. Robins Company, Incorporated
InventorAlbert D. Cale, Jr.
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Abstract
N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides having the formula: ##STR1## wherein R is alkyl and R.sup.1 is hydrogen, aminocarbonyl and trifluoromethyl having central nervous system activity particularly anti-convulsant activity, are disclosed.
Claims21
A compound selected from N-lower-alkyl 3-phenoxy-1-azetidinecarboxamides having the formula:
- ##STR4## wherein R is lower alkyl and R.sup.1 is hydrogen, aminocarbonyl or trifluoromethyl.
A process which comprises orally administering to a living animal body for its anit-convulsant effect an effective amount of a compound selected from the group consisting of N-lower-alkyl 3-phenoxy-1-azetidinecarboxamides of the formula:
- ##STR5## wherein R is lower alkyl and R.sup.1 is hydrogen, aminocarbonyl or trifluoromethyl in admixture with a pharmaceutically acceptable carrier.
An anti-convulsant composition comprising (a) an effective amount of a compound of the formula:
- ##STR6## wherein R is lower alkyl, and R.sup.1 is hydrogen, aminocarbonyl, or trifluoromethyl, and (b) a pharmaceutically acceptable carrier therefor.
Dependencies are inferred from the claim text.