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US 4,226,806 AGranted
7-[(Sulfomethyl)phenyl]acetamidocephalosporin derivatives
AssigneeYeda Research and Development Co. Ltd.
InventorsFortuna Haviv, Abraham Patchornik
Life of this patent
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Abstract
Novel cephalosporin compounds of the following formula are useful as antibiotic agents: ##STR1##
Claims5
A compound of the formula ##STR13## wherein Y is hydrogen, chlorine, bromine, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or an alkoxy group of from 1 to 4 carbon atoms, Z is a bond, oxygen or sulfur;
- W is selected from hydrogen, methyl, amino, hydroxy, SO.sub.3 H, or COOR.sub.4 wherein R.sub.4 is selected from hydrogen or 5-indanyl with the proviso that when Z is oxygen or sulfur, W is other than hydroxy, or an acid halide thereof, with the proviso that when the compound is the acid halide, W is other than COOH.
A compound of the formula ##STR14## wherein Y is hydrogen, chlorine, bromine, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or an alkoxy group of from 1 to 4 carbon atoms, Z is a bond, oxygen or sulfur;
- W is selected from hydrogen, methyl, amino, hydroxy, SO.sub.3 H, or COOR.sub.4 wherein R.sub.4 is selected from hydrogen or 5-indanyl with the proviso that when Z is oxygen or sulfur, W is other than hydroxy.
Dependencies are inferred from the claim text.