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US 4,226,770 AGranted
Synthesis of steroids
OwnerEmil T. Kaiserinventor
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Abstract
The synthesis of 1.alpha.,25-dihydroxycholesterol, 1.alpha.,25-dihydroxy-7-dehydrocholesterol and 1.alpha.,25-dihydroxycholecalciferol and other sterol derivatives from bile acids. Also the synthesis of 3,6-diketo steroids useful in the production of 1.alpha.,25-dihydroxycholesterol and other sterols which are biologically active or can be converted to biologically active sterols. The invention involves the sterols so produced and the processes by which they are prepared.
Claims18
In a process for preparing a 3,6-diketo steroid compounds, the step of heating a compound having the structure:
- ##STR11## with a metal cyanide, where Q is an aryl or alkyl sulfonyl group to produce the compound having the structure:
- ##STR12##
Dependencies are inferred from the claim text.