Surgical devices of polyesteramides derived from bis-oxamidodiols and dicarboxylic acids
AssigneeEthicon, Inc.
InventorsShalaby W. Shalaby, Dennis D. Jamiolkowski
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Abstract
Alternating esteramide polymers are obtained from the reaction of bis-oxamidodiols such as N,N'-bis(.omega.-hydroxyalkylene)oxamide with a dicarboxylic acid or diesters such as diethyl oxalate, diethyl succinate, diethyl suberate, or dimethyl terephthalate. The polymers are obtained in good yield and have film- and fiber-forming properties. Some polymers are absorbable in biological systems and are useful as absorbable surgical devices. Other of these polymers are nonabsorbable and are useful as textile fibers.
Claims17
A surgical suture comprising an oriented filament of an alternating esteramide polymer having repeating units represented by ##STR4## wherein R is a divalent aliphatic or aromatic hydrocarbon radical having from 3 to about 8 carbon atoms, R' is a divalent hydrocarbon radical having from 1 to about 8 carbon atoms, A is a divalent oxyalkylene radical having from 4 to 8 carbon atoms, m is 0 or 1, n is 0 or 1, and x is the degree of polymerization resulting in a film-forming or fiber-forming polymer.
A surgical prosthesis comprising a sterile fabric composed at least in part of filaments of an alternating esteramide polymer having repeating units represented by ##STR5## wherein R is a divalent aliphatic or aromatic hydrocarbon radical having from 3 to about 8 carbon atoms, R' is a divalent hydrocarbon radical having from 1 to about 8 carbon atoms, A is a divalent oxyalkylene radical having from 4 to 8 carbon atoms, m is 0 or 1, n is 0 or 1, and x is the degree of polymerization resulting in a film-forming or fiber-forming polymer.
A surgical prosthesis comprising a solid surgical aid cast or machined from an alternating esteramide polymer having repeating units represented by ##STR6## wherein R is a divalent aliphatic or aromatic hydrocarbon radical having from 3 to about 8 carbon atoms, R' is a divalent hydrocarbon radical having from 1 to about 8 carbon atoms, A is a divalent oxyalkylene radical having from 4 to 8 carbon atoms, m is 0 or 1, n is 0 or 1, and x is the degree of polymerization resulting in a film-forming or fiber-forming polymer.
Dependencies are inferred from the claim text.