Novel amidoxime derivatives
AssigneeSogo Pharmaceutical Company Limited
InventorsMasataka Kuroki, Sadamitsu Kono, Kazuyuki Shioka
Life of this patent
Estimating the term…
Abstract
Novel amidoxime derivatives having the following structural formula (IV) or (IV'): ##STR1## wherein R.sub.1 represents methyl or ethyl group and R.sub.2 represents hydrogen or methyl group, useful as a raw material for 3-amino-5-methyl isoxazole, are prepared from .beta.-amino crotonitrile. Said isoxazole, useful as an intermediate for various medicines, may be prepared without producing any by-products of isomer.
Claims2
A method for preparing 3-amino-5-methylisoxazole having the formula ##STR3## which comprises treating an amidoxime derivative having formula IV or IV' ##STR4## wherein R.sub.1 is methyl or ethyl, and R.sub.2 is H or methyl, in the presence of a mineral acid in a polar solvent to obtain in one stage said 3-amino-5-methylisoxazole.
Dependencies are inferred from the claim text.