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US 4,225,610 AGranted
Immunoactivators derived from amino thiazoles
AssigneePierre Fabre S.A.
InventorsJean-Pierre Tarayre, Henri Cousse, Gilbert Mouzin, Henri Lauressergues, Silvano Casadio
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Abstract
The present invention concerns new derivatives of 4-phenyl 2-amino thiazole of the formula ##STR1## in which X represents a hydrogen atom, a halogen, a lower alkyl or an alkoxy, R is a hydrogen, a haloalkoxy, a substituted or unsubstituted aryl, a pyridyl, an aryloxy or a carboxy alkyl, having immunomodulating properties, useful in the treatment of rheumatoid arthritis and other ailments requiring immunotherapy.
Claims13
4-phenyl-2-amino thiazoles having the formula:
- ##STR19## in which:
- X represents a hydrogen atom, a halogen, a lower alkyl, or an alkoxy,
- R represents --O--C--(Cl).sub.3 ;
- --O--CH.sub.2 --C(Cl).sub.3 ;
- --O--CH.sub.2 --CH.sub.2 --CH.sub.2 --Br;
- --O--CH.sub.2 --CHBr.sub.2 ;
- or carboxyalkyl.
4 more elements
Dependencies are inferred from the claim text.