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US 4,225,591 AGranted
2,6-Diaminonebularines
AssigneeTakeda Chemical Industries, Ltd.
InventorsRyuji Marumoto, Masao Tanabe, Yoshiyasu Furukawa
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Abstract
Novel N.sup.2 -substituted phenyl-2,6-diaminonebularines of the formula ##STR1## wherein R.sup.1 is halogen, lower alkyl or lower alkoxy and R.sup.2 is hydrogen, halogen, lower alkyl or lower alkoxy, and their acid addition salts have excellent coronary vasodilator action.
Claims7
A compound selected from the group consisting of N.sup.2 -(m-methylphenyl)-2,6-diaminonebularine,
- N.sup.2 -(m-methoxyphenyl)-2,6-diaminonebularine,
- N.sup.2 -(m-chlorophenyl)-2,6-diaminonebularine, and
- N.sup.2 -(m,p-dimethylphenyl)-2,6-diaminonebularine
- or a pharmaceutically acceptable acid addition salt thereof.
1 more element
Dependencies are inferred from the claim text.