Method for preparing a substance having properties against collagen diseases and products obtained
AssigneeSociete Civile Particuliere de Brevets Suffren
InventorJean Valetas
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Abstract
This invention relates to the chemical and pharmaceutical industries. An active agent is extracted from ferns with a water-alcohol mixture. The essential compound is a delta-lactone having 8 carbon atoms, obtained as a monomer and/or as polymers, and which may be under the form of a chelate salt. It is useful mainly as the active substance in drugs for the treatment of diseases accompanied by collagen alterations.
Claims15
A method for preparing a substance having activity against collagen diseases, comprising submitting ferns to a water-alcoholic extraction effected using a water-alcohol mixture containing at least 20% of methanol, ethanol or propanol and purifying the extract by contacting it with activated charcoal or with a similar tannin absorbent.
A pharmaceutically active agent comprising at least one delta-lactone compound having 8 carbon atoms extractible from ferns by water-alcohol extraction, or a salt formed with pharmaceutically acceptable base.
A substance useful as an active agent against collagen alterations, constituted by a C.sub.8 delta-lactone with the following formula ##STR5## as a monomer or chelate salt thereof.
Dependencies are inferred from the claim text.