Process for producing deoxynarasin antibiotics
AssigneeEli Lilly and Company
InventorsWalter M. Nakatsukasa, Gary G. Marconi, Norbert Neuss, Robert L. Hamill
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Abstract
Deoxynarasin antibiotic complex, comprising 20-deoxynarasin and 20-deoxy-epi-17-narasin, is produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 11181. 20-Deoxynarasin and 20-deoxy-epi-17-narasin are separated and isolated by chromatography. The deoxynarasin complex, 20-deoxynarasin and 20-deoxy-epi-17-narasin are antibacterial and anticoccidial agents and also increase feed-utilization efficiency in ruminants.
Claims5
The method of producing the deoxynarasin antibiotic complex which comprises cultivating Streptomyces aureofaciens NRRL 1181 or a deoxynarasin-producing mutant thereof in a culture medium containing assimilable sources of carbohydrate, nitrogen, and inorganic salts under submerged aerobic fermentation conditions until a substantial amount of antiobiotic activity is produced.
Dependencies are inferred from the claim text.