Piperidines morpholines, etc., and fungicidal compositions thereof
AssigneeHoffmann-La Roche Inc.
InventorAlbert Pfiffner
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Abstract
Heterocyclic compounds characterized by the formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, X and z are as hereinafter set forth, prepared, inter alia, by reacting a compound characterized by the formula ##STR2## with an amine characterized by the formula ##STR3## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, X and Y are as hereinafter set forth, are described. The end products are useful as fungicidal agents.
Claims140
A compound of the formula ##STR17## wherein R is alkyl of 4 to 12 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, mono(lower alkyl)-substituted cycloalkyl of 4 to 7 carbon atoms, cycloalkylalkyl of 4 to 12 carbon atoms, phenyl, phenyl-(lower alkyl) of 7 to 12 carbon atoms, or naphthyl-(lower alkyl) of up to 12 carbon atoms in which the phenyl or naphthyl group can be mono- or di-(lower alkyl) substituted;
- R.sub.1, and R.sub.3, independently, are hydrogen or alkyl of 1 to 8 carbon atoms;
- R.sub.2 is methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 8 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or can together form a fused alicyclic or aromatic 6-membered ring;
- provided that when R is tert.-butyl, at least one of R.sub.1 and R.sub.3 is alkyl of 2 to 8 carbon atoms, or at least one of R.sub.4, R.sub.5 and R.sub.6 is alkyl of 5 to 8 carbon atoms;
- X is methylene or an oxygen atom;
- z is zero or 1;
- and the dotted bonds can be hydrogenated or an acid addition salt of a compound which is basic.
An agricultural fungicidal composition comprising an effective amount of at least one compound of the formula ##STR25## wherein R is alkyl of 4 to 12 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, mono(lower alkyl)-substituted cycloalkyl of 4 to 7 carbon atoms, cycloalkylalkyl of 4 to 12 carbon atoms, phenyl, phenyl-(lower alkyl) of 7 to 12 carbon atoms, or naphthyl-(lower alkyl) of up to 12 carbon atoms in which the phenyl or naphthyl group can be mono- or di-(lower alkyl) substituted;
- R.sub.1, and R.sub.3, independently, are hydrogen or alkyl of 1 to 8 carbon atoms;
- R.sub.2 is methyl;
- R.sub.4, R.sub.5 and R.sub.6, independently, are hydrogen or alkyl of 1 to 8 carbon atoms, and two of R.sub.4, R.sub.5 and R.sub.6 can each be bonded to the same carbon atom or can together form a fused alicyclic or aromatic 6-membered ring;
- provided that when R is tert.-butyl, at least one of R.sub.1 and R.sub.3 is alkyl of 2 to 8 carbon atoms, or at least one of R.sub.4, R.sub.5 and R.sub.6 is alkyl of 5 to 8 carbon atoms;
- X is methylene or an oxygen atom;
- z is zero or 1;
- and the dotted bonds can be hydrogenated or an acid addition salt of a compound which is basic.
Dependencies are inferred from the claim text.