Investigating body function
AssigneeThe Radiochemical Centre Limited
InventorsReginald Monks, Anthony L. M. Riley
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Abstract
Body function of a mammal is investigated using a .gamma.-emitting .sup.75 Se or .sup.123m Te labelled derivative of a bile acid or bile salt. Thus bowel function may be investigated by oral administration of the labelled compound followed, after a suitable period of time, by either a whole body count or a faecal count of radioactivity. Preferred bile acids and salts are substituted either at the 19-position or in the C-17 side chain.
Claims9
A method for investigating body function of a mammal, comprising introducing a .gamma.-emitting radioactive Se or Te labelled derivative of a bile acid or a bile salt comprising an amino acid conjugate of a bile acid or a metabolic precursor thereof in to the live mammal, and after the elapse of a suitable period of time determining the distribution of the radioactivity.
Dependencies are inferred from the claim text.