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US 4,196,188 AGranted
Orally administrable form of progesterone
OwnerJean-Louis A. Besinsinventor
Life of this patent
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Abstract
The present invention relates to an orally active pharmaceutical preparation comprised of progesterone, finely ground such that 80% of the progesterone particles are about 1-15 microns in size, suspended in an excipient and contained in capsules. The drug effects increased progestational and contraceptive activity at this particle size.
Claims1
An effective orally administrable soft gelatin capsule essentially containing micronised particles of recrystallized progesterone at least 80% having a particle size of from 5 to less than about 15 microns, in an oil vehicle, said micronized particles having been micronized in said oil phase.
Dependencies are inferred from the claim text.