Retinoic acid derivatives

A derivative of all-trans-retinoic acid selected from the group consisting of:

• (A) esters of all-trans-retinoic acid having the following formula:
• ##STR7## wherein X is a member selected from the group consisting of:
• 2-cyclohexylethyl;
• 10-carbomethoxydecyl;
• 4-hydroxybutyl;
• cholesteryl;
• 4-bromobenzyl;
• ##STR8## (B) esters of all-trans-retinoic acid having the following formula:
• ##STR9## wherein Y is a member selected from the group consisting of:
• cholesteryl;
• phenyl;
• 4-bromophenyl;
• 4-nitrophenyl;
• 4-cyanophenyl;
• and 2,4-dichlorophenyl;
• and
• (C) amides of all-trans-retinoic acid having the following formula:
• ##STR10## wherein Z is a member selected from the group consisting of:
• n-propylamino;
• tert.-butylamino;
• 1,1,3,3-tetramethylbutylamino;
• 4-hydroxyphenylamino;
• 4-carbomethoxy-3-hydroxyphenylamino;
• .beta.-(3,4-dimethoxyphenyl)-ethylamino;
• 2-benzothiazolylamino;
• 1-imidazolyl;
• 1-(2-nicotinoylhydrazolyl);
• 1-benzotriazolyl;
• 1-(1,2,4-triazolyl);
• ##STR11##