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US 4,176,186 AGranted
Quaternary derivatives of noroxymorphone which relieve intestinal immobility
AssigneeBoehringer Ingelheim GmbH
InventorsLeon I. Goldberg, Herbert Merz, Klaus Stockhaus
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Abstract
Compounds of the formula ##STR1## wherein R is allyl or a related radical such as chloroallyl, cyclopropyl-methyl or propargyl, and X is the anion of an acid, especially a chloride, bromide, iodide or methylsulfate anion; the compounds prevent or relieve the intestinal mobility inhibiting side-effects of narcotic analgesics without interfering with the analgesic activity of the latter.
Claims4
A compound of the formula ##STR7## wherein R is allyl, chloroallyl, cyclopropylmethyl or propargyl;
- and
- X is a chloride, bromide, iodide, or methylsulfate anion.
Dependencies are inferred from the claim text.