US 4,170,642 A · Derivatives of kanamycin A

Abstract

Novel derivatives of kanamycin, 1-N-(L-4-amino-2-hydroxy butyryl)-6'-N-alkylkanamycins, have been prepared which possess improved antibacterial activity against gram-positive and gram-negative bacteria including kanamycin-resistant strains.

Claims8

Dependent claims

1-N-(L-4-amino-2-hydroxybutyryl)-6'-N-alkylkanamycin having the formula:

##STR3## wherein R is methyl or ethyl, and the pharmaceutically acceptable acid addition salt thereof.

Dependencies are inferred from the claim text.

Facts

Application

05/557,590Filed 12 Mar 1975 · continuation in part

Priority

JP 49-3154822 Mar 1974

Granted

9 Oct 1979

Term ends

Not estimatedThe source records don’t support an estimate.

Classification4 codes

C07H 15/224
Cyclohexane rings substituted by at least two nitrogen atoms: with only one saccharide radical directly attached to the cyclohexyl radical, e.g.…
C07H 15/23
Attached to adjacent ring-carbon atoms of the cyclohexane rings: with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin,…
C07H 15/234
With at least two saccharide radicals directly attached to the cyclohexane rings: attached to non-adjacent ring carbon atoms of the cyclohexane…
C07H
Sugars

Abstract

Claims8

Dependent claims

1-N-(L-4-amino-2-hydroxybutyryl)-6'-N-alkylkanamycin having the formula:

##STR3## wherein R is methyl or ethyl, and the pharmaceutically acceptable acid addition salt thereof.

Dependencies are inferred from the claim text.

Derivatives of kanamycin A

Life of this patent

Abstract

Claims8

Derivatives of kanamycin A

Life of this patent

Abstract

Claims8