Copolymers of (a) aminimides and (b) vinyl pendant primary halomethy monomers useful for affinity chromatography
AssigneeBoard of Regents, for and on behalf of the University of Florida
InventorJohn C. M. Tsibris
Life of this patent
Estimating the term…
Abstract
A polymer suitable for use in affinity chromatography comprising a polymer f an aminimide and a vinyl compound having at least one pendant halo-methyl group and the said polymer wherein an amine ligand which affords sites for binding in affinity chromatography is coupled to the polymer by reaction with a portion of the pendant halo-methyl groups and the remainder of said pendant halo-methyl groups are reacted with an amine containing a pendant hydrophilic group. The invention also comprises a method of coating a substrate with the above polymer and a method of fractionating mixtures by affinity chromatography employing the above polymer as an adsorbent.
Claims2
A polymer suitable for use in affinity chromatography comprising an addition copolymer of (1) at least one aminimide of the structural formula:
- ##STR8## wherein R.sub.1 and R.sub.2 are the same or different and represent lower alkyl;
- R.sub.3 represents an organic group, and
- Z represents the residue of a polymerizable vinyl compound,
- and (2) a vinyl compound having at least one pendant primary halomethyl group.
Dependencies are inferred from the claim text.