Fungicidally active antibiotic from Streptomyces tendae Ettlinger
AssigneeBayer Aktiengesellschaft
InventorsUrsula Dahn, Hanspaul Hagenmaier, Helmut Hohne, Wilfried Konig, Hans Scheinpflug, Hans Zahner
Life of this patent
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Abstract
The new antibiotic Nikkomycin is produced by culturing the strain Streptomyces tendae Ettlinger et al Tu 901 in a nutrient medium at a pH of about 5.5 to 8 under aerobic conditions and isolation by cation exchange from the culture filtrate, followed by elution. The antibiotic is believed to have the structural formula ##STR1## and is characterized by fungicidal activity.
Claims2
A process for the preparation of the antibiotic Nikkomycin which comprising culturing the strain Streptomyces tendae Ettlinger et al Tu 901 in an aqueous nutrient medium containing a source of carbon, nitrogen, hydrogen and oxygen under aerobic conditions at about 18.degree. to 37.degree. C. and at a pH of about 5.5 to 8 and isolating Nikkomycin from the culture.
Dependencies are inferred from the claim text.