US 4,155,991 A · Vaginal ring

Abstract

A composite vaginal ring containing a safe and effective amount of a pharmaceutically active medicament, which comprises: (a) a major supporting vaginal ring consisting essentially of a physiologically acceptable synthetic resin and having at least a portion of the annular surface thereof adapted to mate with corresponding minor, medicament-containing vaginal ring segment; and (b) at least one minor, medicament-containing vaginal ring segment adapted to mate with the modified annular surface of said major supporting vaginal ring and consisting essentially of a safe and effective amount of a pharmaceutically active amount of a nonionic, lipophilic drug dissolved or uniformly suspended in an elastomeric, cross-linked LTV linear dimethylpolysiloxane resin.

Claims19

Dependent claims

A composite vaginal ring containing a safe and effective amount of a pharmaceutically active medicament, consisting essentially of:

(a) a supporting, medicament-free vaginal ring consisting essentially of a physiologically acceptable synthetic resin and having a continuous encircling pocket-like indentation along the inner edge of the annular surface along the central plane thereof adapted to mate with a corresponding smaller, medicament-containing inner encircling annular minor vaginal ring segment;
and
(b) a smaller, vaginal medicament-containing inner encircling annular minor vaginal ring adapted to mate with the continuous encircling pocket-like indentation in the modified annular surface of said supporting, medicament-free vaginal ring along the central plane thereof and consisting essentially of a safe and effective amount of a pharmaceutically active nonionic, lipophilic vaginal drug dissolved or uniformly suspended in an elastomeric, crosslinked LTV linear dimethylpolysiloxane resin.

Dependencies are inferred from the claim text.

Vaginal ring

Life of this patent

Vaginal ring

Life of this patent

Abstract

Claims19