Combination vaccine for swine dysentery and method of use
AssigneesIowa State University Research Foundation, Inc., Chromalloy American Corporation
InventorsDelbert L. Harris, Robert A. Goodnow, Robert D. Glock, Joann M. Kinyon
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Abstract
A combination vaccine for increasing the resistance of swine to dysentery infection comprises killed cells of a virulent isolate of Treponema hyodysenteriae in combination with concentrated killed cells of Bacteroides vulgatus, or Fusobacterium necrophorum, or mixtures thereof. This combination vaccine can be adapted for either oral or parenteral administration. For parenteral administration preferably only Bacteroides vulgatus is used in combination with Treponema hyodysenteriae. The oral vaccine is enteric-coated.
Claims10
An oral preparation for increasing the resistance of swine to dysentery infection, comprising enteric-coated orally-administrable pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae in combination with concentrated killed cells of other bacteria selected from the group consisting of Bacteroides vulgatus, Fusobacterium necrophorum, and mixtures thereof, at least one of said other bacteria being present in an amount of from 0.25 to 2 parts by weight (dry basis) per part of said Treponema hyodysenteriae.
The method of increasing the resistance of field-raised swine to dysentery infection, comprising orally administering to the swine prior to their contracting the infection a plurality of doses of enteric-coated pellets containing concentrated killed cells of Treponema hyodysenteriae in combination with concentrated killed cells of other bacteria selected from the group consisting of Bacteroides vulgatus, Fusobacterium necrophorum, and mixtures thereof, each of said doses providing at least 3 milligrams (dry basis) of said Treponema hyodysenteriae cells together with from 0.25 to 2 parts by weight (dry basis) of at least one of said other bacteria.
Dependencies are inferred from the claim text.