Methods and applications of preparative scale chromatography
AssigneeNational Research Development Corporation
InventorCourtenay S. G. Phillips
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Abstract
A preparative scale chromatographic method in which a mixture is chromatographically fractionated on a sorbent material by the displacing action of a sorbate which is thermally displaced through the material by a heated zone advancing through the material to leave behind sorbent material substantially free of said sorbate. In an application of particular interest, at least one component of the mixture is produced by catalytic reaction of one or more thermally displaced sorbates induced by the heated zone of sorbent material.
Claims13
A chromatographic method for catalytically reacting at least one sorbate component to form a mixture of sorbate components and fractionating said mixture, comprising:
- (a) providing a flow path of a catalytic sorbent having different affinities for the sorbate components of said mixture;
- (b) feeding a starting material comprising said at least one sorbate component into said flow path of sorbent;
- and
- (c) catalytically reacting said at least one sorbate component to form said mixture of sorbate components, and fractionating said sorbate components into an abutting succession of components for said sorbent, by thermally displacing said at least one sorbate component through said sorbent in advance of a heat zone moving relative to said sorbent, the mixture being fractionated into sorbate components in the advancing relatively cool area of sorbent ahead of said heat zone, the amount of all sorbate components remaining in said sorbent behind said heat zone being relatively insignificant.
A chromatographic method for catalytically reacting at least one sorbate component comprising paraffins to increase the branching of said paraffins and form a mixture of sorbate components and for fractionating said mixture, comprising:
- (a) providing a flow path of a catalytic sorbent having different affinities for the sorbate components of said mixture, said sorbent comprising gamma alumina containing a minor amount of platinum chlorinated with carbon tetrachloride at elevated temperatures;
- (b) feeding a starting material comprising said at least one sorbate component into said flow path of sorbent;
- and
- (c) catalytically reacting said at least one sorbate component to increase the branching of said paraffins and to form said mixture of sorbate components, and fractionating said sorbate components into an abutting succession of components for said sorbent, by thermally displacing said at least one sorbate component through said sorbent in advance of a heat zone moving relative to said sorbent, the mixture being fractionated into sorbate components in the advancing relatively cool area of sorbant ahead of said heat zone, the amount of all sorbate components remaining in said sorbent behind said heat zone being relatively insignificant.
Dependencies are inferred from the claim text.