Alkyl 5,6-dichloro-3,4-dihydro-2(1H)-iminoquinazoline-3-acetate hydrohalides
AssigneeBristol-Myers Company
InventorsThomas A. Jenks, Warren N. Beverung, Jr., Richard A. Partyka
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Abstract
The known blood platelet antiaggregative agent 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one is prepared in high yield via an improved process involving a novel intermediate of the Formula ##STR1## in which R.sup.1 is (lower)alkyl and X is bromo, chloro or iodo. Two processes for the preparation of compounds of the Formula III are disclosed, one of which involves the novel intermediate ##STR2##
Claims16
A compound of the formula ##STR14## wherein R.sup.1 is (lower)alkyl and X is chloro, bromo or iodo.
The compound of the formula ##STR15##
The compound of the formula ##STR16##
The compound of the formula ##STR17##
The compound of the formula ##STR18##
The compound of the formula ##STR19##
The compound of the formula ##STR20##
The compound of the formula ##STR21##
Dependencies are inferred from the claim text.