2-Aminocycloaliphatic amide compounds

A compound of the formula ##STR83## wherein the .about. at the 1-position of the cycloaliphatic ring denotes trans-stereoconfiguration of the 1-position substituent with respect to the substituent in position 2 of the same cycloaliphatic ring;

• R is C.sub.1 to C.sub.3 -alkyl;
• R.sub.1 and R.sub.2, taken separately, are C.sub.1 to C.sub.3 -alkyl, or when R.sub.1 is C.sub.1 to C.sub.3 -alkyl, R.sub.2 is C.sub.1 to C.sub.6 -alkyl, -CH.sub.2 CF.sub.3, C.sub.3 to C.sub.6 -(allylic)alkenyl, C.sub.2 to C.sub.5 -hydroxyalkyl, C.sub.3 to C.sub.6 -cycloalkyl, C.sub.3 to C.sub.4 -cycloalkylmethyl, phenyl-C.sub.1 to C.sub.3 -alkyl, or R.sub.1 and R.sub.2 taken together with the nitrogen to which they are bonded complete a saturated, monocyclic, mononitrogen heterocyclic ring containing only carbon and nitrogen ring atoms and containing from 3 to 4 carbon atoms;
• said saturated monocyclic nitrogen heterocyclic rings having 3 to 4 ring carbon atoms permissively being substituted in the 3-position of the ring with hydroxy, C.sub.1 to C.sub.3 -alkyloxy, or C.sub.1 to C.sub.3 -alkanoyloxy;
• or N-piperazinyl ring, permissively substituted on the N'-nitrogen with a C.sub.1 to C.sub.3 -alkyl;
• R.sub.3 is hydrogen or methyl;
• R.sub.4 is hydrogen or methyl, or R.sub.3 and R.sub.4 can be taken together with the carbon to which they are bonded to complete a cyclopropylene ring;
• m is 1 to 4 and is 2 to 4 only when R.sub.3 and R.sub.4 are both hydrogen;
• n is 2 to 4;
• and
• Q is 1-naphthyl, 2-naphthyl or ##STR84## wherein each of X, Y and Z is hydrogen, a halogen having an atomic number of from 9 to 35, trifluoromethyl, C.sub.2 to C.sub.3 -alkyl, C.sub.1 to C.sub.3 -alkyloxy, azido or phenyl, and at least one of X, Y and Z is a substituent other than hydrogen, and when one of X, Y and Z is azido, phenyl, C.sub.1 to C.sub.3 -alkyloxy or trifluoromethyl, the remaining X, Y and Z moieties are hydrogen, and the pharmaceutically acceptable salts thereof.