Deoxynarasin antibiotics
AssigneeEli Lilly and Company
InventorsWalter M. Nakatsukasa, Gary G. Marconi, Norbert Neuss, Robert L. Hamill
Life of this patent
Estimating the term…
Abstract
Deoxynarasin antibiotic complex, comprising 20-deoxynarasin and 20-deoxy-epi-17-narasin, is produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 11181. 20-Deoxynarasin and 20-deoxy-epi-17-narasin are separated and isolated by chromatography. The deoxynarasin complex, 20-deoxynarasin and 20-deoxy-epi-17-narasin are antibacterial and anticoccidial agents and also increase feed-utilization efficiency in ruminants.
Claims5
20-Deoxynarasin which has the following formula:
- ##STR4## and its pharmaceutically acceptable salts.
20-Deoxy-epi-17-narasin which has the following formula:
- ##STR5## and its pharmaceutically acceptable salts.
The deoxynarasin antibiotic complex comprising 20-deoxynarasin and 20-deoxy-epi-17-narasin which is produced by cultivating Streptomyces aureofaciens NRRL 11181 or a mutant thereof in a culture medium containing assimilable sources of carbohydrate, nitrogen, and inorganic salts under submerged aerobic fermentation conditions until a substantial amount of antibiotic activity is produced.
Dependencies are inferred from the claim text.