Malonato platinum anti-tumor compounds

Platinum coordination compounds having the formula:

• [Pt(II)A.sub.x ((OOC).sub.2 --CRR.sub.1)]
• wherein:
• x = 1 or 2;
• R and R.sub.1 are selected from the group consisting of H, lower alkyl, aryl, aralkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxy, OH, or combine with the carbon atom to form a cycloalkyl or cycloalkenyl group;
• when x = 1, A is HR.sub.2 N--CHR.sub.3 --CHR.sub.4 --NR.sub.5 H and when x = 2, A is H.sub.2 NR.sub.6 or an amino acid, wherein R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are the same or different and are selected from the group consisting of H, CH.sub.3, C.sub.2 H.sub.5, hydroxy and lower alkoxy, provided that R.sub.2 and R.sub.5 may also be aryl or aralkyl and each R.sub.6 is the same or different and is selected from the group consisting of H, lower alkyl, aryl, aralkyl, hydroxy lower alkyl, hydroxyl- and alkoxylamines, and alkoxyl alkyl amines.