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US 4,139,589 AGranted
Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
OwnerMonique Beringer, Siegfried Woltmanninventors
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Abstract
Multi-zone pharmaceutical tablets are produced by compressing the contents of a tablet mold. The contents include a granular chewing gum mass and a non-plastic tablet mass, or a chewing gum insert in the recess of a multi-layer non-plastic tablet mass. At least one zone of the tablet, preferably the chewing gum mass, contains a pharmaceutically active ingredient.
Claims3
A process for the manufacture of an inlaid tablet, comprising the steps of incorporating into a plastic chewing gum mass a sustained-release ingredient selected from the group consisting of anti-smoking alum and antitussives;
- incorporating into a non-plastic tablet mass a substantially immediate-release pharmaceutically active ingredient selected from the group consisting of quinine, fennel oil and eucalyptus oil;
- and respectively converting said chewing gum mass and said tablet mass into the core and the outer layer of the inlaid tablet.
Dependencies are inferred from the claim text.