Perfluoro polycyclic compounds for use as synthetic blood and perfusion media
AssigneesSun Ventures, Inc., Children's Hospital Medical Center
InventorsRobert E. Moore, Leland C. Clark, Jr.
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Abstract
Novel emulsions of non-aromatizable perfluorinated compounds are useful as blood substitutes or as perfusion materials for the storage of organs such as kidneys prior to transplant. The compounds employed are polycyclic compounds and emulsions prepared from the perfluorinated derivatives thereof possess extremely high stability, zero or extremely low ultimate residue in the body, and a vapor pressure which is just about right for use in the body without adverse effects thereon.
Claims26
An artificial blood comprising an emulsion of a non-aromatizable perfluorinated material in water, the amount of water being greater than 40% by volume, said emulsion containing a non-toxic emulsifier and a perfluorinated C.sub.9 -C.sub.18 polycyclic hydrocarbon containing at least two bridgehead carbon atoms linked through a bridge containing at least one carbon atom.
Dependencies are inferred from the claim text.