Thieno [2,3-c] and [3,2-c] pyridines

Process for the preparation of pyridine derivatives having the following formulae (I) and (II):

• ##STR7## in which R.sup.1 represents a radical selected from hydrogen, lower alkyl and aralkyl optionally substituted in the aromatic nucleus with at least a group selected from halogen, hydroxy, nitro, amino, cyano, carboxy, alkoxycarbonyl, lower alkyl, lower alkoxy and trifluoromethyl;
• R.sup.2 represents a group selected from hydrogen and lower alkyl;
• and
• R.sup.3 represents a group selected from hydrogen and at least a substituent selected from halogen, hydroxy, lower alkyl and lower alkoxy,
• and their pharmaceutically acceptable inorganic and organic acid addition salts, comprising cyclizing a compound selected from the compounds of the formulae (III) and (IV), respectively:
• ##STR8## by heating in acidic medium.

Therapeutic composition having an anti-inflammatory and blood-platelet aggregation inhibiting activity, comprising, as active ingredient, an efficient amount of a pyridine derivative selected from the compounds having the following formulae (I) and (II):

• ##STR9## in which R.sup.1 represents a radical selected from hydrogen, lower alkyl and aralkyl optionally substituted in the aromatic nucleus with at least a group selected from halogen, hydroxy, nitro, amino, cyano, carboxy, alkoxycarbonyl, lower alkyl, lower alkoxy and trifluoromethyl;
• R.sup.2 represents a group selected from hydrogen and lower alkyl;
• and
• R.sup.3 represents a group selected from hydrogen and at least a substituent selected from halogen, hydroxy, lower alkyl and lower alkoxy,
• and their pharmaceutically acceptable inorganic and organic acid addition salts, together with pharmaceutically acceptable excipients.