Thiazolylacetamido cephalosporin type compounds

A pharmaceutical composition which contains a medicinally effective amount of a member of the group consisting of (a) a cephem compound of the formula ##STR25## wherein R.sup.1 represents amino, protected amino, hydroxy or protected hydroxy,

• R.sup.2 represents amino, protected amino, hydroxy, protected hydroxy or the group ##STR26## represents a group of the formula ##STR27## wherein R.sup.5 is hydroxy or protected hydroxy, R.sup.3 represents hydrogen or methoxy,
• R.sup.4 represents heterocyclic thio wherein heterocyclic is a 5 to 6 membered hetero ring containing 1 to 4 hetero atoms from the group of oxygen, sulfur and nitrogen, said ring being unsubstituted or substituted by lower alkyl, lower alkoxy, halogen, haloalkyl, amino, mercapto, hydroxy, carbamoyl or carboxy, and
• R.sup.8 represents hydrogen or halogen,
• (b) a pharmaceutically acceptable salt thereof, and
• (c) a pharmaceutically acceptable ester of the 4-position carboxyl group selected from the group consisting of alkoxymethyl, .alpha.-alkoxyethyl, .alpha.-alkoxy-.alpha.-substituted methyl, alkylthiomethyl, acyloxymethyl and .alpha.-acyloxy-.alpha.-substituted methyl esters together with at least one pharmaceutically acceptable carrier, said composition being administrable in a dosage unit form.