Process for the fermentation production of ergoline derivatives

A method for obtaining ergoline derivatives by a fermentation process, the said derivatives including alkaloids and 9,10-dihydrogenated alkaloids of the ergotoxine group and including ergometrine, and

• the said process comprising
• growing conidiospores under saprophytic conditions from a strain of Claviceps purpurea (Fr.) Tul. deposited under number IMET PA 130 at the Institute for Microbiology and Experimental Therapy at Jena, German Democratic Republic, then employing these spores as inoculum in a submerged culture in a culture medium under aerobic conditions, and at the completion of the cultivation extracting the formed alkaloids from the filtrate or from the mycelium or directly from the culture medium, and if 9,10-dihydrogenated alkaloids are wanted then subjecting the recovered alkaloids to a 9,10-dihydrogenation.