Back to results
US 4,085,117 AGranted
6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids
AssigneeMerck & Co., Inc.
InventorsEdward J. Cragoe, Jr., Otto W. Woltersdorf, Jr., William F. Hoffman
Life of this patent
Estimating the term…
Abstract
6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids, the pharmaceutically acceptable salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuric and antihypertensive activity.
Claims9
A compound having the formula:
- ##STR7## wherein X is halo, methyl or hydrogen;
- Y is halo or methyl and
- R is thienyl or a substituted thienyl wherein the substituent is halo or methyl, and
- the non-toxic pharmaceutically acceptable salt derivative thereof.
1 more element
A compound of the formula:
- ##STR8## wherein X is halo, methyl or hydrogen;
- Y is halo or methyl;
- R is selected from the group consisting of 2-thienyl, 3-thienyl or 5-methyl-2-thienyl and
- the non-toxic pharmaceutically acceptable salt derivatives thereof.
1 more element
Dependencies are inferred from the claim text.