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US 4,081,402 AGranted
Hydrophilic absorbents
AssigneeNational Patent Development Corporation
InventorsDidya D. Levy, Samuel H. Ronel
Life of this patent
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Abstract
Products are prepared of solid hydrogel matrixes having entrapped therein high-surface area sorbent materials, preferably activated carbon. The entrapped absorbent has an effective surface area no greater than about 1% of the actual surface area of the sorbent material, e.g., activated carbon per se, preferably not over 0.001%. The products are particularly useful in radioimmunoassay for antigens.
Claims17
An article of manufacture comprising a hydrophilic polymer matrix and particulate microporous sorbent dispersed therein,
- A. said article being characterized by the following properties:
- (i) solid, (ii) insoluble in deionized water and lower alkanols, (iii) normally shape-retaining in the dehydrated state as well as in the fully hydrated state, (iv) water-swellable to the extent that is possesses a deionized water-uptake value of from 200% to 2200%, based on the weight of the dehydrated article, (v) a partition coefficient of at least 2, (vi) an average molecular weight diffusion limitation of about 10,000 Daltons, and (vii) a gross external surface area no greater than about one percent of the total surface area of total microporous sorbent dispersed therein;
- B. said polymer (i) having an average molecular weight greater than about 40,000, and (ii) a deionized water-uptake value in the range of from 60% to 4000%, based on the weight of said polymer;
- and
- C. the concentration of said sorbent being in the range of from 0.01 to 50 weight percent, based on the weight of said polymer.
2 more elements
Dependencies are inferred from the claim text.