Process for producing 2-amino-(2)-thiazoline-4-carboxylic acid
AssigneeAjinomoto Co., Inc.
InventorsKazushi Togo, Fumihide Tamura, Naohiko Yasuda, Takehiko Ichikawa, Konosuke Sano, Keizo Matsuda, Koji Mitsugi
Life of this patent
Estimating the term…
Abstract
2-Amino-(2)-thiazoline-4-carboxylic acid is prepared by dehydrochlorinating S-(.beta.-carboxy-.beta.-chloroethyl) isothiourea by adding it to an aqueous medium maintained at a pH ranging from 5.5 to 7.5 with an alkali.
Claims7
A process for producing 2-amino-(2)-thiazoline-4-carboxylic acid which comprises dehydrochlorinating S-(.beta.-carboxy-.beta.-chloroethyl) isothiourea by adding it to an aqueous medium maintained at a pH ranging from 5.5 to 7.5 with an alkali.
A process for producing 2-amino-(2)-thiazoline-4-carboxylic acid, which comprises:
- preparing an alkyl .alpha.-chloracrylate by dehydrochlorinating an alkyl .alpha., .beta.-dichloropropionate in water in the presence of an alkali;
- preparing a S-(.beta.-carboxy-.beta.-chloroethyl) isothiourea by reacting said alkyl .alpha.-chloroacrylate with thiourea in water in the presence of a mineral acid;
- and
- dehydrochlorinating said S-(.beta.-carboxy-.beta.-chloroethyl) isothiourea by adding said S-(.beta.-carboxy-.beta.-chloroethyl) isothiourea to an aqueous medium maintained at a pH ranging from 5.5 to 7.5 with an alkali.
Dependencies are inferred from the claim text.