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US 4,071,680 AGranted
5'-Deoxy-5-fluoropyrimidine nucleosides
AssigneeHoffmann-La Roche Inc.
InventorAlan Frederick Cook
Life of this patent
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Abstract
Novel 5'-deoxy-5-fluoropyrimidine nucleosides are potent anti-tumor agents. Preferred compounds are 5'-deoxy-5-fluorocytidine and 5'-deoxy-5-fluorouridine.
Claims4
A 5'-deoxy-5-fluoropyrimidine nucleoside selected from the group consisting of 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine and the pharmaceutically acceptable acid addition salts thereof.
A 5'-deoxy-2',3'-O-isopropylidene-5-fluoropyrimidine-nucleoside selected from 5'-deoxy-2',3'-O-isopropylidene-5-fluorocytidine and 5'-deoxy-2',3'-O-isopropylidene5-fluorouridine.
Dependencies are inferred from the claim text.