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US 4,071,622 AGranted
Treatment of a mammary or DMBA inducible tumor
AssigneeAbbott Laboratories
InventorsEdwin Samuel Johnson, John Hunter Seely
Life of this patent
Estimating the term…
Abstract
Certain nonapeptide amides were found which, upon administration at daily dosages of from about 1-200 .mu.g/kg to warm-blooded animals, cause regression of DMBA-inducible or mammary tumors without causing adverse effects on healthy tissues.
Claims9
The method of reducing the size of a mammary or DMBA-inducible tumor in a warm-blooded animal by administering to an animal having a mammary or DMBA-inducible tumor an effective daily amount to reduce the size of such a tumor of a nonapeptide of the formula
- L-pGlu-L-His-L-Trp-L-Ser-L-Tyr-X-L-Leu-L-Arg-L-Pro-NH-C.sub.2 H.sub.5
- wherein X denotes the optically active D-form of Tyr, Trp or Phe.
Dependencies are inferred from the claim text.