Test composition and device for determining peroxidatively active substances
AssigneeMiles Laboratories, Inc.
InventorCharles Tak Wai Lam
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Abstract
A test composition and device are disclosed for determining the presence of peroxidatively active substances, such as hemoglobin, in a test sample. Also disclosed is a one-dip method for preparing the device. The test composition comprises: An organic hydroperoxide, An indicator capable of producing a detectable response in the presence of a hydroperoxide and a peroxidatively active substance, and A borate ester having the structure ##STR1## in which m, n and p, same or different, are integers of 1 to about 4. The test device comprises a carrier matrix incorporated with the test composition.
Claims30
A test composition for detecting the presence of a peroxidatively active substance in a sample comprising
- an organic hydroperoxide,
- an indicator capable of producing a detectable response in the presence of a hydroperoxide and a peroxidatively active substance, and
- a borate ester having the structure ##STR3## in which m, n and p, same or different, are integers of 1 to about 4.
A test composition for determining the presence of a peroxidatively active constituent in a sample, the composition comprising cumene hydroperoxide, o-tolidine, and triethanolamine borate.
A test device for determining the presence of a constituent in a sample wherein a carrier matrix is incorporated with a test composition comprising
- an organic hydroperoxide,
- an indicator capable of forming a detectable response in the presence of a hydroperoxide and a peroxidatively active substance, and
- a borate ester having the structure ##STR4## in which m, n and p, same or different, are integers of 1 to about 4.
A test device for determining the presence of a peroxidatively active constituent in a sample, the device having a carrier matrix incorporated with a test composition comprising cumene hydroperoxide, o-tolidine and triethanolamine borate.
A one-dip process for preparing a test device for determining the presence of a peroxidatively active constituent in a sample comprising the steps of
- preparing a mixture of a test composition comprising an organic hydroperoxide, an indicator capable of producing a detectable response in the presence of a hydroperoxide and a peroxidatively active substance, and a borate ester having the structure ##STR5## in which m, n and p, same or different, are integers from 1 to about 4, and a suitable liquid diluent, and
- incorporating said mixture with a carrier matrix.
A one-dip process for preparing a test device for determining the presence of a peroxidatively active constituent in a sample, comprising the steps of
- preparing a mixture of a test composition comprising cumene hydroperoxide, o-tolidine and triethanolamine borate, and a suitable liquid diluent, and
- incorporating the test compound with a matrix.
Dependencies are inferred from the claim text.