Back to results
US 4,070,496 AGranted
Phosphine oxides having a physiological cooling effect
AssigneeWilkinson Sword Limited
InventorsDavid G. Rowsell, David J. Spring
Life of this patent
Estimating the term…
Abstract
Compounds and compositions are disclosed having a physiological cooling action on the skin. The compositions contain as the active ingredient certain phosphine oxides. The compositions disclosed include toilet and cosmetic preparations, e.g. toilet water, after-shave lotions, soaps, cosmetic creams and lotions, dentifrices and cleansing tissues, and tobacco and tobacco preparations.
Claims10
In a manufactured consumer product for application to or consumption by the human body, said product comprising (a) a topically administrable or orally ingestible carrier and one or more of the following:
- a flavourant, colourant, odourant, antiseptic, antacid or analgesic, and (b) a compound capable of stimulating the cold receptors of the nervous system in the surface tissues of the body when brought into contact therewith by application or consumption of the said product, the improvement which comprises using as the cold receptor stimulating compound, an effective amount of a cold receptor stimulating phosphine oxide of the formula ##STR3## where R.sub.1 is a straight chain alkyl group having from 4-8 carbon atoms inclusive;
- R.sub.2 is a branched chain alkyl group having from 3-5 carbon atoms inclusive;
- and
- R.sub.3 is an alkyl group having from 3-6 carbon atoms inclusive or cyclopentyl;
- R.sub.1, r.sub.2 and R.sub.3 together providing a total of from 13-16 carbon atoms.
2 more elements
Dependencies are inferred from the claim text.