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US 4,070,378 AGranted
Synthesis cyclopentanol
AssigneeHoffmann-La Roche Inc.
InventorsFrank Kienzle, Perry Rosen
Life of this patent
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Abstract
Process for synthesizing the lactone, (dl) 3,3a beta-4,5-6,6a beta-hexahydro-4beta(3-hydroxyl-1-trans-octenyl)-5alpha-hydroxy-2-oxo-2H-c yclopenta[b]furan, a known intermediate for producing prostaglandin E.sub.2 and F.sub.2.alpha. and a process for preparing 11-desoxy and 11-alkyl prostaglandins from dihydroresorcyclic acid.
Claims2
A compound of the formula:
- ##STR28## wherein R.sub.4 lower alkyl;
- and R.sub.12 is lower alkanoyloxy, benzoyloxy, tetrahydropyranyloxy, benzyloxy, trityloxy, 4-methoxy-5,6-dihydro-2H-pyranyloxy, benzyhydryloxy or trimethylsilyloxy
- or enantiomers or racemates thereof.
Dependencies are inferred from the claim text.