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US 4,070,376 AGranted
Antibiotic 1745A/X and methods for the production thereof
AssigneeHoffmann-La Roche Inc.
InventorsRonald A. LeMahieu, Richard W. Kierstead, David L. Pruess
Life of this patent
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Abstract
A new antibiotic, designated as antibiotic 1745A/X, is produced by the fermentation of the known microorganism Streptomyces antibioticus, ATCC 11891, using the novel compound erythronolide A oxime as the substrate. This new antibiotic is useful as an antibacterial agent.
Claims1
A process to produce a compound of the formula ##STR5## which comprises A. reacting a compound of the formula ##STR6## with hydrogen fluoride in an inert aromatic base B. neutralizing the resultant product of (A) and
- C. extracting and titurating the product of (B) to produce the final product.
Dependencies are inferred from the claim text.